Total 337 cases too liver biopsy specimens and 98 autopsy cases of hepatic diseases
obtained at the National Medical Center during the period of 1958 to 1968 were
histopathologically examined with statistical analysis for international classification of
diseases and correlation between clinical diagnosis and histopathological diagnosis was
made.
As the result of present study the following conclusions were obtained.
1) By sex, number of male is dominant than female in both biopsy 229 cases (male),
108 cases (Female) 2. 1 : 1, and autopsy cases 72(%ale), 26(Female) 2.8 : 1.
2) Among the groups of hepatic lesions cirrhosis is 80.5% (M 4l. 6%, F 38.9%) with
highest incidence in biopsy material and average age is 34.5 years. Identical findings are
seen in autopsy cases with 57 cases (M 40, F 17) out of 98 cases with the range of
55.6% (M) and 65.4% (F).
3) Post hepatitic cirrhosis is highest among the cirrhotic groups of biopsy material
with 88 cases (M 66, F 22) out of total cirrhosis cases of 137(M 95, F 42) and portal 22
cases (15 M, 7 F), post necrotic 15 cases (9 M, 6 F), biliary 7 cases (4 M,3 F) as in
decreasing order with exceptional 1 case of nutritional Cirrhosis.
4) Average age of tumor is 44. 1 years and somewhat higher than that of cirrhosis
34. 5 years. Tumors among the biopsy material revealed highest incidence of hepatoma
61 cases, extra bile duct ca. 66 cases, and cholangioma 8 cases in decreasing order.
5) In autopsy material age distribution and frequency of hepatic diseases were mostly
similar to that of the biopsy material, however, abscesses were comparatively higher in
cadaver material. Post hepatitic cirrhosis was 36 cases out of 137 cases and 16 cases of
post necrotic cirrhosis was next to the highest incidence.
6) Analytic pilot study for various histopathologic findings to evaluate the grouping of
the hepatic lesions (biopsy) without knowing of previous clinico-pathologic diagnosis or
laboratory findings showed no remarkable or significant difference among the disease
groups.
7) Correlation between clinical and pathologic diagnosis showed considerable
percentage of difference. The difference in abscess and hepatitis was only 9.1%.
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